HPLC Column, RP C4 Butyl, 3um, 4.0mm ID x 100mm Length, 100A. Cogent Brand. 1 EA. Special Order Item.

Additional Information:

Cogent RP C4 Butyl™ is a reversed-phase HPLC stationary phase designed for the separation of hydrophobic to moderately hydrophobic compounds. Manufactured using a traditional butyl (C4) bonded phase on ultra-high purity silica and fully double end capped, it provides excellent reproducibility, reliable peak shape, and balanced retention characteristics. As a USP L26 equivalent phase, it is commonly used as an alternative for compendial methods and for applications where lower hydrophobic retention than C8 or C18 phases is preferred.

68304-10P-4 is an HPLC column packed with 3 µm RP C4 Butyl™ particles featuring a 100 Å pore size in a 4.0 mm ID x 100 mm format. The 100 mm length provides greater resolution and peak capacity than shorter 50 mm columns, while the 3 µm particles deliver improved efficiency and sharper peaks compared to traditional 5 µm packings. Typical operating flow rates are approximately 0.8–1.5 mL/min depending on mobile phase composition, temperature, and system configuration.

This column is particularly useful for hydrophobic and neutral compounds analyzed by reversed-phase HPLC. The C4 chemistry provides lower retention than C8 phases, making it advantageous when faster elution and shorter run times are desired without sacrificing chromatographic performance.

Key Benefits

  • RP C4 Butyl™ stationary phase

  • USP L26 equivalent chemistry

  • Fully double end capped

  • Traditional butyl (C4) bonded phase

  • Ultra-high purity silica support

  • 3 µm particle size

  • Greater efficiency than 5 µm columns

  • Improved peak capacity

  • Excellent balance of speed and resolution

  • Lower retention than C8 columns

Typical Applications

  • USP L26 methods

  • Reversed-phase HPLC

  • Small molecule analysis

  • Hydrophobic compound analysis

  • Neutral compound analysis

  • Pharmaceutical analysis

  • Method development

  • Quality control testing

  • Routine analytical methods

  • Impurity profiling

Specifications

  • Product Type: HPLC Column

  • Stationary Phase: RP C4 Butyl™

  • USP Classification: L26

  • Chromatography Mode: Reversed Phase

  • Bonded Phase: Butyl (C4)

  • Endcapping: Fully Double End Capped

  • Particle Size: 3 µm

  • Pore Size: 100 Å

  • Column Dimensions: 4.0 mm ID x 100 mm

  • Length: 100 mm

  • Typical Flow Rate: 0.8–1.5 mL/min

  • Brand: Cogent

Special Order Item Information

Important Notes

  • Suitable for conventional HPLC systems

  • 3 µm particles provide higher efficiency and sharper peaks than comparable 5 µm columns

  • Generates higher backpressure than larger particle columns

  • The 100 mm length provides greater resolution and peak capacity than 50 mm columns

  • Lower retention than comparable C8 stationary phases

  • Well suited for hydrophobic and neutral compounds

  • Commonly used as an alternative for USP L26 methods

  • This is a Special Order Item


 

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